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Journal article

Eosinophils determine dermal thickening and water loss in an MC903 model of atopic dermatitis

Abstract:

Atopic dermatitis (AD) is a highly debilitating disease with significant health impacts worldwide. It has been a difficult disease to treat because of the wide spectrum of clinical manifestations. Therefore, the current clinical management strategies are nonspecific. Previous studies have documented that AD disease progression is precipitated by a combination of skin barrier dysfunction, itch, and immune dysregulation. However, the precise roles played by effector cells and cytokines have not...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jid.2018.06.168

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
ORCID:
0000-0002-2505-5222
Publisher:
Elsevier
Journal:
Journal of Investigative Dermatology More from this journal
Volume:
138
Issue:
12
Pages:
2606-2616
Publication date:
2018-07-02
Acceptance date:
2018-06-03
DOI:
EISSN:
1523-1747
ISSN:
0022-202X
Pmid:
29964034
Language:
English
Keywords:
Pubs id:
1327744
Local pid:
pubs:1327744
Deposit date:
2023-02-07

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