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Is vascular endothelial growth factor a useful biomarker in giant cell arteritis?

Abstract:

To assess the performance of circulating vascular endothelial growth factor (VEGF) levels as a tool for diagnosing giant cell arteritis (GCA) in a cohort of patients referred for assessment of suspected GCA.We selected 298 patients recruited to the multicentre study Temporal Artery Biopsy versus Ultrasound in diagnosis of suspected GCA (TABUL). In a random subset of 26 biopsy-proven GCA cases and 26 controls, serum from weeks 0, 2 and 26 was analysed for VEGF concentration using ELISA. VEGF c...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/rmdopen-2016-000353

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More from this funder
Funding agency for:
Luqmani, R
Grant:
08/64/01
More from this funder
Funding agency for:
Goodfellow, N
Grant:
Academic Clinical Fellowship
More from this funder
Funding agency for:
Goodfellow, N
Grant:
Academic Clinical Fellowship
Publisher:
BMJ Publishing Group Publisher's website
Journal:
RMD Open Journal website
Volume:
3
Issue:
1
Article number:
e000353
Publication date:
2017-03-29
Acceptance date:
2017-01-03
DOI:
ISSN:
2056-5933
Pmid:
28405470
Language:
English
Keywords:
Pubs id:
pubs:690886
UUID:
uuid:03abc0b7-e81f-4138-8be0-949d0e607cfd
Local pid:
pubs:690886
Source identifiers:
690886
Deposit date:
2017-10-03

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