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STXBP1-associated neurodevelopmental disorder: a comparative study of behavioural characteristics

Abstract:

BACKGROUND:De novo loss of function mutations in STXBP1 are a relatively common cause of epilepsy and intellectual disability (ID). However, little is known about the types and severities of behavioural features associated with this genetic diagnosis. METHODS:To address this, we collected systematic phenotyping data encompassing neurological, developmental, and behavioural characteristics. Participants were 14 individuals with STXBP1-associated neurodevelopmental disorder, ascertained from cl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s11689-019-9278-9

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Oxford college:
St Catherine's College
Role:
Author
ORCID:
0000-0002-6371-8875
Publisher:
BioMed Central Publisher's website
Journal:
Journal of Neurodevelopmental Disorders Journal website
Volume:
11
Issue:
1
Article number:
17
Publication date:
2019-08-06
Acceptance date:
2019-07-22
DOI:
EISSN:
1866-1955
ISSN:
1866-1947
Pmid:
31387522
Language:
English
Keywords:
Pubs id:
pubs:1046234
UUID:
uuid:03a47d02-e537-42f3-8776-8161f54690c9
Local pid:
pubs:1046234
Source identifiers:
1046234
Deposit date:
2019-10-21

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