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Autophagy dictates metabolism and differentiation of inflammatory immune cells

Abstract:

The role of macroautophagy/autophagy, a conserved lysosomal degradation pathway, during cellular differentiation has been well studied over the last decade. Particularly, evidence for its role during immune cell differentiation is growing. Despite the description of a variety of dramatic immune phenotypes in tissue-specific autophagy knockout models, the underlying mechanisms are still under debate. One of the proposed mechanisms is the impact of autophagy on the altered metabolic states duri...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/15548627.2017.1362525

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Somerville College
Role:
Author
Publisher:
Taylor and Francis Publisher's website
Journal:
Autophagy Journal website
Volume:
14
Issue:
2
Pages:
199-206
Publication date:
2017-08-14
Acceptance date:
2017-07-18
DOI:
EISSN:
1554-8635
ISSN:
1554-8627
Source identifiers:
709067
Keywords:
Pubs id:
pubs:709067
UUID:
uuid:03905041-44c1-41a6-8e57-d4a77dc2ee8b
Local pid:
pubs:709067
Deposit date:
2017-07-24

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