- Abstract:
-
The effect of alteplase on patient survival after ischaemic stroke is the subject of debate. We report the effect of intravenous alteplase on long-term survival after ischaemic stroke of participants in the Third International Stroke Trial (IST-3).In IST-3, done at 156 hospitals in 12 countries (Australia, Europe, and the UK), participants (aged >18 years) were randomly assigned with a telephone voice-activated or web-based system in a 1:1 ratio to treatment with intravenous 0·9 mg/kg alte...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(pdf, 310.8KB)
-
- Publisher copy:
- 10.1016/s1474-4422(16)30139-9
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Neurology Journal website
- Volume:
- 15
- Issue:
- 10
- Pages:
- 1028-1034
- Publication date:
- 2016-07-20
- Acceptance date:
- 2016-06-13
- DOI:
- EISSN:
-
1474-4465
- ISSN:
-
1474-4422
- Pubs id:
-
pubs:636470
- URN:
-
uri:036da67b-cad2-4802-95f6-66d8c476a37a
- UUID:
-
uuid:036da67b-cad2-4802-95f6-66d8c476a37a
- Local pid:
- pubs:636470
- Language:
- English
- Keywords:
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2016
- Notes:
- © 2016 Elsevier Ltd. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/S1474-4422(16)30139-9
Journal article
Effects of alteplase on survival after ischaemic stroke (IST-3): 3 year follow-up of a randomised, controlled, open-label trial
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