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A single-cell genome reveals diplonemid-like ancestry of kinetoplastid mitochondrial gene structure

Abstract:

Euglenozoa comprises euglenids, kinetoplastids, and diplonemids, with each group exhibiting different and highly unusual mitochondrial genome organizations. Although they are sister groups, kinetoplastids and diplonemids have very distinct mitochondrial genome architectures, requiring widespread insertion/deletion RNA editing and extensive trans-splicing, respectively, in order to generate functional transcripts. The evolutionary history by which these differing processes arose remains unclea...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1098/rstb.2019.0100

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Role:
Author
ORCID:
0000-0002-4426-9533
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Role:
Author
ORCID:
0000-0002-4607-2064
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Department:
ZOOLOGY
Sub department:
Zoology
Role:
Author
ORCID:
0000-0003-3669-7463
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Role:
Author
ORCID:
0000-0002-7987-1700
Publisher:
Royal Society Publisher's website
Journal:
Philosophical Transactions B: Biological Sciences Journal website
Volume:
374
Issue:
1786
Article number:
20190100
Publication date:
2019-10-07
Acceptance date:
2019-06-15
DOI:
EISSN:
1471-2970
ISSN:
0962-8436
Pmid:
31587636
Language:
English
Keywords:
Subjects:
Pubs id:
1101954
Local pid:
pubs:1101954
Deposit date:
2020-06-04

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