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Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study

Abstract:

Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST). As the implementation costs and technical barriers fall, whole-genome sequencing (WGS) has emerged as a ‘one-stop’ test for epidemiological and predictive AST results. Few published comparisons exist for the myriad analytical pipelines used for predicting AMR. To address this, we performed an inter-laboratory st...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1099/mgen.0.000335

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Role:
Author
ORCID:
0000-0001-5001-1945
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Role:
Author
ORCID:
0000-0001-8721-5386
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Role:
Author
ORCID:
0000-0001-8985-9265
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Publisher:
Microbiology Society Publisher's website
Journal:
Microbial Genomics Journal website
Volume:
6
Issue:
2
Article number:
335
Publication date:
2020-02-12
Acceptance date:
2020-01-17
DOI:
EISSN:
2057-5858
Pmid:
32048983
Language:
English
Keywords:
Pubs id:
1088009
Local pid:
pubs:1088009
Deposit date:
2020-05-08

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