Journal article icon

Journal article

The importance of DNA methylation in prostate cancer development.

Abstract:

After briefly reviewing the nature of DNA methylation, its general role in cancer and the tools available to interrogate it, we consider the literature surrounding DNA methylation as relating to prostate cancer. Specific consideration is given to recurrent alterations. A list of frequently reported genes is synthesized from 17 studies that have reported on methylation changes in malignant prostate tissue, and we chart the timing of those changes in the diseases history through amalgamation...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1016/j.jsbmb.2016.04.009

Authors


More by this author
Role:
Author
ORCID:
0000-0003-2314-4843
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
Oxford college:
Linacre College
Role:
Author
ORCID:
0000-0001-5347-5083
European Research Council More from this funder
Norwegian Research Council More from this funder
Southern and Eastern Norway Regional Health Authority More from this funder
Belfast-Manchester Movember Centre of Excellence More from this funder
Expand funders...
Publisher:
Elsevier Publisher's website
Journal:
Journal of Steroid Biochemistry and Molecular Biology Journal website
Volume:
166
Pages:
1-15
Publication date:
2016-04-05
Acceptance date:
2016-04-17
DOI:
EISSN:
1879-1220
ISSN:
0960-0760
Pubs id:
pubs:817480
URN:
uri:023e0bfc-97d6-4cc6-b3ea-60d1ef4c1228
UUID:
uuid:023e0bfc-97d6-4cc6-b3ea-60d1ef4c1228
Local pid:
pubs:817480

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP