Journal article icon

Journal article

Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells.

Abstract:

Hepatitis C virus (HCV) replicates primarily in the liver, but HCV RNA has been observed in association with other tissues and cells including B and T lymphocytes, monocytes, and dendritic cells. We have taken advantage of a recently described, robust system that fully recapitulates HCV entry, replication and virus production in vitro to re-examine the issue of HCV infection of blood cell subsets. The HCV replicase inhibitor 2'C-methyl adenosine was used to distinguish HCV RNA replication fro...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/hep.22550

Authors


Marukian, S More by this author
Ritola, KD More by this author
Expand authors...
Journal:
Hepatology (Baltimore, Md.)
Volume:
48
Issue:
6
Pages:
1843-1850
Publication date:
2008-12-29
DOI:
EISSN:
1527-3350
ISSN:
0270-9139
URN:
uuid:022c345f-84f7-4483-a21e-3cdf84523284
Source identifiers:
426224
Local pid:
pubs:426224

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP