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Fluoxetine does not enhance visual perceptual learning and triazolam specifically impairs learning transfer

Abstract:

The selective serotonin reuptake inhibitor fluoxetine significantly enhances adult visual cortex plasticity within the rat. This effect is related to decreased gamma-aminobutyric acid (GABA) mediated inhibition and identifies fluoxetine as a potential agent for enhancing plasticity in the adult human brain. We tested the hypothesis that fluoxetine would enhance visual perceptual learning of a motion direction discrimination (MDD) task in humans. We also investigated (1) the effect of fluoxeti...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fnhum.2016.00532

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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Natural Sciences and Engineering Research Council of Canada More from this funder
Marsden Fund of New Zealand More from this funder
Publisher:
Frontiers Publisher's website
Journal:
Frontiers in Human Neuroscience Journal website
Volume:
10
Pages:
532
Publication date:
2016-10-01
Acceptance date:
2016-10-06
DOI:
ISSN:
1662-5161
Source identifiers:
679159
Keywords:
Pubs id:
pubs:679159
UUID:
uuid:022b945b-1ca5-423f-86d7-efc913b2a193
Local pid:
pubs:679159
Deposit date:
2017-10-25

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