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Radiation Dose-Response for Risk of Myocardial Infarction in Breast Cancer Survivors

Abstract:

Purpose: Previous reports suggest that radiation therapy for breast cancer (BC) can cause ischemic heart disease, with the radiation-related risk increasing linearly with mean whole heart dose (MWHD). This study aimed to validate these findings in younger BC patients and to investigate additional risk factors for radiation-related myocardial infarction (MI).

Methods and Materials: A nested case-control study was conducted within a cohort of BC survivors treated during 1970 to 2009. ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Authors


Jacobse, JN More by this author
Boekel, NB More by this author
Schaapveld, M More by this author
Hauptmann, M More by this author
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Publisher:
Elsevier Publisher's website
Journal:
International Journal of Radiation Oncology*Biology*Physics Journal website
Volume:
103
Issue:
3
Pages:
595-604
Publication date:
2018-10-29
Acceptance date:
2018-10-19
DOI:
EISSN:
1879-355X
ISSN:
0360-3016
Pubs id:
pubs:943686
URN:
uri:0222ca2c-20f9-48a2-ab01-b4c142ddc25e
UUID:
uuid:0222ca2c-20f9-48a2-ab01-b4c142ddc25e
Local pid:
pubs:943686
Language:
English

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