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Determinants of plasma methylmalonic acid in a large population: implications for assessment of vitamin B12 status

Abstract:

BACKGROUND: Methylmalonic acid (MMA) in plasma or serum is widely used for assessment of vitamin B(12) status. However, data are sparse regarding factors, besides renal function, that may influence MMA concentrations. We searched for important determinants of plasma MMA in the general population. METHODS: In 6946 middle-aged (47-49 years) and elderly (71-74 years) individuals from the Hordaland Homocysteine Study in Norway, we collected anthropometric measurements, lifestyle data, and plasma...

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Publication status:
Published
Peer review status:
Peer reviewed

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Department:
Oxford, MSD, Pharmacology
Role:
Author
Publisher:
American Association for Clinical Chemistry Publisher's website
Journal:
Clinical chemistry Journal website
Volume:
55
Issue:
12
Pages:
2198-2206
Publication date:
2009-12-10
DOI:
EISSN:
1530-8561
ISSN:
0009-9147
Pubs id:
pubs:195501
URN:
uri:01ec4046-ee4f-41cd-8f38-6186c50b2707
UUID:
uuid:01ec4046-ee4f-41cd-8f38-6186c50b2707
Local pid:
pubs:195501
Language:
English
Keywords:

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