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Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions.

Abstract:
We have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplogroup frequencies were compared between 3 microdeletion classes and the non-deleted infertile males. Deletions arise on many different haplotypic backgrounds. No statistically significant differences in frequency were seen, although the small number of AZFa deletions lay predominantly on one branch of the Y haplotype tree.
Publication status:
Published

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Publisher copy:
10.1007/bf03343792

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author


Journal:
Journal of endocrinological investigation More from this journal
Volume:
23
Issue:
10
Pages:
671-676
Publication date:
2000-11-01
DOI:
EISSN:
1720-8386
ISSN:
0391-4097


Language:
English
Keywords:
Pubs id:
pubs:31785
UUID:
uuid:01d5030f-ec6a-4240-a31d-673757e58f93
Local pid:
pubs:31785
Source identifiers:
31785
Deposit date:
2012-12-19
ARK identifier:

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