Extracellular vesicles: biology and emerging therapeutic opportunities.

Journal article

Within the past decade, extracellular vesicles have emerged as important mediators of intercellular communication, being involved in the transmission of biological signals between cells in both prokaryotes and higher eukaryotes to regulate a diverse range of biological processes. In addition, pathophysiological roles for extracellular vesicles are beginning to be recognized in diseases including cancer, infectious diseases and neurodegenerative disorders, highlighting potential novel targets ...

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Authors: Andaloussi, S; Mäger, I; Breakefield, X; Wood, M

• Publication status: Published
• Journal: Nature reviews. Drug discovery
• Volume: 12
• Issue: 5
• Pages: 347-357
• Publication date: 2013-05-01
• DOI: 10.1038/nrd3978
• EISSN: 1474-1784
• ISSN: 1474-1776
• Language: English
• Keywords: Extracellular Space; Exosomes; Cell-Derived Microparticles; Drug Therapy; Drug Delivery Systems; Humans; Cell Communication; Translational Medical Research