Journal article

Studies on the transformation of nitrosugars into branched chain iminosugars. Part II: Synthesis of (3R,4R,5R,6S)-2,2-bis(hydroxymethyl)azepane-3,4,5,6-tetraol

Abstract:: The first stereocontrolled synthesis of (3R,4R,5R,6S)-2,2-bis-(hydroxymethyl)azepane-3,4,5,6-tetraol is described herein. The method involves a novel double Henry reaction of the 3,5-di-O-benzyl-6-deoxy-1,2-O-isopropylidene-6-nitro-α-d-glucofuranose with formaldehyde followed by a reductive ring closure to give the first branched 1,6-dideoxy-1,6-heptitol described. © 2008 Elsevier Ltd. All rights reserved.

Publication status:: Published

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APA Style

Otero, J., Estevez, A., Soengas, R., Estevez, J., Nash, R., Fleet, G., & Estevez, R. (2008). Studies on the transformation of nitrosugars into branched chain iminosugars. Part II: Synthesis of (3R,4R,5R,6S)-2,2-bis(hydroxymethyl)azepane-3,4,5,6-tetraol. TETRAHEDRON-ASYMMETRY, 19(21), 2443–2446.

MLA Style

Otero, J, et al. “Studies on the Transformation of Nitrosugars into Branched Chain Iminosugars. Part II: Synthesis of (3R,4R,5R,6S)-2,2-Bis(Hydroxymethyl)Azepane-3,4,5,6-Tetraol.” TETRAHEDRON-ASYMMETRY, vol. 19, no. 21, 2008, pp. 2443–46.

Chicago Style

Otero, J, A Estevez, R Soengas, et al. 2008. “Studies on the Transformation of Nitrosugars into Branched Chain Iminosugars. Part II: Synthesis of (3R,4R,5R,6S)-2,2-Bis(Hydroxymethyl)Azepane-3,4,5,6-Tetraol.” TETRAHEDRON-ASYMMETRY 19 (21): 2443–46.
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Publisher copy:: 10.1016/j.tetasy.2008.10.027

Authors

+ Otero, J More by this author

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+ Estevez, A More by this author

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+ Soengas, R More by this author

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+ Estevez, J More by this author

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+ Nash, R More by this author

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Journal:: TETRAHEDRON-ASYMMETRY More from this journal
Volume:: 19
Issue:: 21
Pages:: 2443-2446
Publication date:: 2008-11-03
DOI:: 10.1016/j.tetasy.2008.10.027
EISSN:: 1362-511X
ISSN:: 0957-4166

Language:: English
Pubs id:: pubs:41011
UUID:: uuid:01bb79f1-fd68-4a4a-95d2-8f7a6d00b4c6
Local pid:: pubs:41011
Source identifiers:: 41011
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_01bb79f1fd684a4a95d28f7a6d00b4c6

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Copyright date:: 2008

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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