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Characterizing microstructural tissue properties in Multiple Sclerosis with diffusion MRI at 7 T and 3 T: The impact of the experimental design

Abstract:

The recent introduction of advanced magnetic resonance (MR) imaging techniques to characterize focal and global degeneration in multiple sclerosis (MS), like the Composite Hindered and Restricted Model of Diffusion, or CHARMED, diffusional kurtosis imaging (DKI) and Neurite Orientation Dispersion and Density Imaging (NODDI) made available new tools to image axonal pathology non-invasively in vivo. These methods already showed greater sensitivity and specificity compared to conventional diffus...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Institution:
University of Oxford
Division:
Medical Sciences
Department:
Clinical Neurosciences
Role:
Author
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Role:
Author
ORCID:
0000-0002-1231-1928
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Publisher:
Elsevier Publisher's website
Journal:
Neuroscience Journal website
Volume:
403
Pages:
17-26
Publication date:
2018-04-07
Acceptance date:
2018-03-28
DOI:
EISSN:
1873-7544
ISSN:
0306-4522
Pubs id:
pubs:843572
URN:
uri:01ac31c0-6fdb-42bc-a518-8244451fd707
UUID:
uuid:01ac31c0-6fdb-42bc-a518-8244451fd707
Local pid:
pubs:843572

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