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Recent developments in vascular endothelial cell transient receptor potential channels.

Abstract:

Among the 28 identified and unique mammalian TRP (transient receptor potential) channel isoforms, at least 19 are expressed in vascular endothelial cells. These channels appear to participate in a diverse range of vascular functions, including control of vascular tone, regulation of vascular permeability, mechanosensing, secretion, angiogenesis, endothelial cell proliferation, and endothelial cell apoptosis and death. Malfunction of these channels may result in disorders of the human cardiova...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology, BHF Centre of Research Excellence
Journal:
Circulation research
Volume:
97
Issue:
9
Pages:
853-863
Publication date:
2005-10-05
DOI:
EISSN:
1524-4571
ISSN:
0009-7330
URN:
uuid:01a6e3d8-91fb-4723-b559-e1c4d34ac7e5
Source identifiers:
106201
Local pid:
pubs:106201

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