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Journal article

Marker selection for genetic case-control association studies.

Abstract:

Association studies can focus on candidate gene(s), a particular genomic region, or adopt a genome-wide association approach, each of which has implications for marker selection. The strategy for marker selection will affect the statistical power of the study to detect a disease association and is a crucial element of study design. The abundant single nucleotide polymorphisms (SNPs) are the markers of choice in genetic case-control association studies. The genotypes of neighboring SNPs are of...

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Publication status:
Published

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Publisher copy:
10.1038/nprot.2009.38

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Journal:
Nature protocols
Volume:
4
Issue:
5
Pages:
743-752
Publication date:
2009-01-01
DOI:
EISSN:
1750-2799
ISSN:
1754-2189
URN:
uuid:0166a589-992f-47be-bfc1-43628aa07f7c
Source identifiers:
34699
Local pid:
pubs:34699

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