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A randomized placebo-controlled trial of adefovir dipivoxil in advanced HIV infection: the ADHOC trial.

Abstract:

OBJECTIVES: To assess the efficacy and safety of adefovir dipivoxil (ADV) added to stable background antiretroviral therapy (ART) in HIV-infected individuals with advanced HIV disease. METHODS: ADHOC was a randomized, double-blind, placebo-controlled, international multicentre trial. Three hundred and one individuals with CD4 cell counts < 100 cells/microL or < 200 cells/microL with nadir < 50 cells/microL were allocated to receive either 120 mg ADV (subsequently 60 mg) (n = 161) or...

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Journal:
HIV medicine
Volume:
3
Issue:
4
Pages:
229-238
Publication date:
2002-10-05
DOI:
EISSN:
1468-1293
ISSN:
1464-2662
URN:
uuid:015de556-fc4c-4a55-a36c-08038dfa8d65
Source identifiers:
444420
Local pid:
pubs:444420

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