Journal article

Asymmetric synthesis of aldol products derived from unsymmetrical ketones: assignment of the absolute configuration of antibody aldol products

Abstract:: Compounds 1-7 are the products formed by aldol condensation of p-nitrobenzaldehyde with a series of unsymmetrical ketones, the reaction occurring at the less substituted carbon. The asymmetric synthesis of 1-7 using the Evans's asymmetric aldol methodology is described in detail. These syntheses were completed to allow us to assign the absolute configuration of products 1-3, obtained in a single step in the presence of the aldolase I antibody 84G3. © 2002 Elsevier Science Ltd. All rights reserved.

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Maggiotti, V., Wong, J., Razet, R., Cowley, A., & Gouverneur, V. (2002). Asymmetric synthesis of aldol products derived from unsymmetrical ketones: assignment of the absolute configuration of antibody aldol products. TETRAHEDRON-ASYMMETRY, 13(16), 1789–1798.

MLA Style

Maggiotti, V, et al. “Asymmetric Synthesis of Aldol Products Derived from Unsymmetrical Ketones: Assignment of the Absolute Configuration of Antibody Aldol Products.” TETRAHEDRON-ASYMMETRY, vol. 13, no. 16, 2002, pp. 1789–98.

Chicago Style

Maggiotti, V, J Wong, R Razet, A Cowley, and V Gouverneur. 2002. “Asymmetric Synthesis of Aldol Products Derived from Unsymmetrical Ketones: Assignment of the Absolute Configuration of Antibody Aldol Products.” TETRAHEDRON-ASYMMETRY 13 (16): 1789–98.
Print

Access Document

Publisher copy:: 10.1016/S0957-4166(02)00410-X

Authors

+ Maggiotti, V More by this author

Role:: Author

+ Wong, J More by this author

Role:: Author

+ Razet, R More by this author

Role:: Author

+ Cowley, A More by this author

Role:: Author

+ Gouverneur, V More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

Journal:: TETRAHEDRON-ASYMMETRY More from this journal
Volume:: 13
Issue:: 16
Pages:: 1789-1798
Publication date:: 2002-08-27
DOI:: 10.1016/S0957-4166(02)00410-X
ISSN:: 0957-4166

Language:: English
Pubs id:: pubs:38438
UUID:: uuid:0154186c-4db5-486f-8664-478d6334d8ab
Local pid:: pubs:38438
Source identifiers:: 38438
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_0154186c4db5486f8664478d6334d8ab

Terms of use

Copyright date:: 2002

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP