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FGF8 isoform b expression in human prostate cancer.

Abstract:

Overexpression of fibroblast growth factor 8 (FGF8) mRNA has been previously described in prostate cancer. Of its four isoforms, FGF8b is thought to be the most important in carcinogenesis. We hypothesised that immunodetection of FGF8b in archival prostate cancer specimens is of potential prognostic value. Using a selected cohort of prostate tumours from transurethral (n=30) and radical prostatectomies (n=59), an optimised protocol for FGF8b immunoreactivity was used to corroborate expression...

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Publication status:
Published

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Publisher copy:
10.1038/sj.bjc.6600875

Authors


Gnanapragasam, VJ More by this author
Robinson, MC More by this author
Robson, CN More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences, Biomedical Research Centre
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Journal:
British journal of cancer
Volume:
88
Issue:
9
Pages:
1432-1438
Publication date:
2003-05-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:014b165f-fbe7-4dde-b027-c726db7af27a
Source identifiers:
120616
Local pid:
pubs:120616

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