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Combined high-resolution genotyping and geospatial analysis reveals modes of endemic urban typhoid fever transmission

Abstract:

Typhoid is a systemic infection caused by Salmonella Typhi and Salmonella Paratyphi A, human-restricted bacteria that are transmitted faeco-orally. Salmonella Typhi and S. Paratyphi A are clonal, and their limited genetic diversity has precluded the identification of long-term transmission networks in areas with a high disease burden. To improve our understanding of typhoid transmission we have taken a novel approach, performing a longitudinal spatial case-control study for typhoid in Nepal, ...

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Publisher copy:
10.1098/rsob.110008

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Journal:
Open Biology
Volume:
1
Issue:
OCTOBER
Publication date:
2011-01-01
DOI:
EISSN:
2046-2441
URN:
uuid:01454c97-6595-4a56-9eaf-f1ea876a4e79
Source identifiers:
348842
Local pid:
pubs:348842

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