- Abstract:
-
Optical detection of individual proteins requires fluorescent labeling. Cavity and plasmonic methodologies enhance single molecule signatures in the absence of any labels but have struggled to demonstrate routine and quantitative single protein detection. Here, we used interferometric scattering microscopy not only to detect but also to image and nanometrically track the motion of single myosin 5a heavy meromyosin molecules without the use of labels or any nanoscopic amplification. Together w...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1021/nl500234t
-
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- Publisher:
- American Chemical Society
- Journal:
- Nano letters
- Volume:
- 14
- Issue:
- 4
- Pages:
- 2065-2070
- Publication date:
- 2014-01-01
- DOI:
- EISSN:
-
1530-6992
- ISSN:
-
1530-6984
- URN:
-
uuid:0142cb70-3001-4b3a-9def-dfceeddc5176
- Source identifiers:
-
451161
- Local pid:
- pubs:451161
- Language:
- English
- Keywords:
- Copyright date:
- 2014
Journal article
Label-free, all-optical detection, imaging, and tracking of a single protein.
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