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A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes.

Abstract:

The human genes encoding the "ovalbumin" subgroup of closely related serine proteinase inhibitors (serpins) are located at 18q21.3 and 6p25. Those at 6p25 include proteinase inhibitor 6 (PI-6; gene symbol PI6), proteinase inhibitor 9 (PI-9; gene symbol PI9) and monocyte neutrophil elastase inhibitor (M/NEI; gene symbol ELANH2). Here we describe the fine mapping of these genes to a 200-kb region of chromosome 6 that includes the markers WI-8835 and D6S1338, and the establishment of the gene or...

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Publication status:
Published

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Publisher copy:
10.1159/000015118

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Journal:
Cytogenetics and cell genetics
Volume:
82
Issue:
3-4
Pages:
273-277
Publication date:
1998-01-01
DOI:
EISSN:
1424-859X
ISSN:
0301-0171
URN:
uuid:01427680-2fa5-49e6-b495-a3fa15f07fe8
Source identifiers:
71873
Local pid:
pubs:71873

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