Journal article

Chemical modification and micropatterning of Si(100) with oligonucleotides

Abstract:: A method for the reliable attachment of oligonucleotides to silicon (1 0 0) surfaces in patterns is described. UV light exposure of silicon (1 0 0) coated with alkenes functionalized with carboxylic acid groups and derivatives results in covalent attachment to the silicon surface. The carboxyl-terminated (and derivatives) surfaces act as a substrate for the chemistry of the subsequent attachment of oligonucleotides. Illustrated are our results gained for optimisation of the surface attachment chemistry and the characterisation of the surface with scanning electron microscopy, epifluorescence microscopy and ellipsometry. © 2004 Elsevier B.V. All rights reserved.

Publication status:: Published

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APA Style

Yin, H., Brown, T., Greef, R., Wilkinson, J., & Melvin, T. (2004). Chemical modification and micropatterning of Si(100) with oligonucleotides. MICROELECTRONIC ENGINEERING, 73-4, 830–836.

MLA Style

Yin, H, et al. “Chemical Modification and Micropatterning of Si(100) with Oligonucleotides.” MICROELECTRONIC ENGINEERING, vols. 73-4, 2004, pp. 830–36.

Chicago Style

Yin, H, T Brown, R Greef, J Wilkinson, and T Melvin. 2004. “Chemical Modification and Micropatterning of Si(100) with Oligonucleotides.” MICROELECTRONIC ENGINEERING 73-4: 830–36.
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Publisher copy:: 10.1016/j.mee.2004.03.060

Authors

+ Yin, H More by this author

Role:: Author

+ Brown, T More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Greef, R More by this author

Role:: Author

+ Wilkinson, J More by this author

Role:: Author

+ Melvin, T More by this author

Role:: Author

Journal:: MICROELECTRONIC ENGINEERING More from this journal
Volume:: 73-4
Pages:: 830-836
Publication date:: 2004-06-01
DOI:: 10.1016/j.mee.2004.03.060
ISSN:: 0167-9317

Language:: English
Keywords:: silicon functionalisation

surface attachment chemistry

conjugation

oligonucleotide
Pubs id:: pubs:400213
UUID:: uuid:01424077-0927-4efe-b6d1-cd1d36b1fc2a
Local pid:: pubs:400213
Source identifiers:: 400213
Deposit date:: 2013-11-16
ARK identifier:: ark:/29072/ora_0142407709274efeb6d1cd1d36b1fc2a

Terms of use

Copyright date:: 2004

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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