Journal article icon

Journal article

A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake.

Abstract:

The class A macrophage scavenger receptors (SR-A) are macrophage-specific trimeric integral membrane glycoproteins that have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. There are two forms of the receptor that have been previously cloned, and both are generated by alternative splicing of a single gene. Here we report the cloning of a third, alternatively spliced isoform of the human SR...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School, BHF Centre of Research Excellence
Journal:
Journal of lipid research
Volume:
39
Issue:
3
Pages:
531-543
Publication date:
1998-03-05
ISSN:
0022-2275
URN:
uuid:013f7db7-73d8-4a65-b205-9d8629ad97e7
Source identifiers:
5010
Local pid:
pubs:5010

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP