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Journal article

Nutrient supply and intervertebral disc metabolism.

Abstract:

The metabolic environment of disc cells is governed by the avascular nature of the tissue. Because cellular energy metabolism occurs mainly through glycolysis, the disc cells require glucose for survival and produce lactic acid at high rates. Oxygen is also necessary for cellular activity, although not for survival; its pathway of utilization is unclear. Because the tissues are avascular, disc cells depend on the blood supply at the margins of the discs for their nutrients. The nucleus and in...

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Publication status:
Published

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Publisher copy:
10.2106/jbjs.e.01290

Authors


Journal:
The Journal of bone and joint surgery. American volume
Volume:
88 Suppl 2
Issue:
SUPPL. 2
Pages:
30-35
Publication date:
2006-04-05
DOI:
EISSN:
1535-1386
ISSN:
0021-9355
URN:
uuid:0106097e-9de2-42bc-bb0b-6157aa816f52
Source identifiers:
238538
Local pid:
pubs:238538

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