Journal article
MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage
- Abstract:
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Macrophage receptor with collagenous structure (MARCO) has an important role in the phagocytosis of Mycobacterium tuberculosis (M. tuberculosis). We hypothesized that MARCO polymorphisms are associated with phagocytosis, tuberculosis (TB) disease susceptibility and presentation, and infecting lineage. We used a human cellular model to examine how MARCO genotype mediates the immune response; a case-control study to investigate tuberculosis host genetic susceptibility; and a host-pathogen genet...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 729.7KB, Terms of use)
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- Publisher copy:
- 10.1038/gene.2016.43
Authors
Funding
+ Wellcome Trust
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Grant:
TrainingFellowshipinPublicHealth
TropicalMedicineawarded
toNTTT(097124/Z/11/Z
Bibliographic Details
- Publisher:
- Nature Publishing Group
- Journal:
- Genes and Immunity More from this journal
- Volume:
- 17
- Issue:
- 7
- Pages:
- 419–425
- Publication date:
- 2016-11-17
- Acceptance date:
- 2016-10-17
- DOI:
- EISSN:
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1476-5470
- ISSN:
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1466-4879
Item Description
- Language:
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English
- Pubs id:
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pubs:660180
- UUID:
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uuid:00869f77-49dc-4289-98ba-750db55da256
- Local pid:
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pubs:660180
- Source identifiers:
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660180
- Deposit date:
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2016-11-28
Terms of use
- Copyright holder:
- Thuong et al
- Copyright date:
- 2016
- Notes:
- This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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