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Journal article

Short-term escitalopram treatment normalizes aberrant self-referential processing in major depressive disorder

Abstract:

Background: Increased self-focus and negative self-concept play an important role in depression. Antidepressants influence self-referential processing in healthy volunteers, but their function in self-processing of depressed patients remains unknown.

Methods: Thirty-two depressed patients were randomly allocated to receive either escitalopram 10 mg or placebo for one week. After one week, neural responses to positive and negative self-referential adjectives and neutral control stim...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jad.2018.04.096

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
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Funding agency for:
Nummenmaa, L
Grant:
250935
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Funding agency for:
Ekelund, J
Grant:
250935
Publisher:
Elsevier Publisher's website
Journal:
Journal of Affective Disorders Journal website
Volume:
236
Pages:
222-229
Publication date:
2018-04-22
Acceptance date:
2018-04-08
DOI:
EISSN:
1573-2517
ISSN:
0165-0327
Source identifiers:
848077
Keywords:
Pubs id:
pubs:848077
UUID:
uuid:0085afda-4db1-41ca-905b-0ff468d70a41
Local pid:
pubs:848077
Deposit date:
2018-05-18

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