- Abstract:
-
Background: Most reported human H5N1 viral infections have been severe and were detected after hospital admission. A case ascertainment bias may therefore exist, with mild cases or asymptomatic infections going undetected. We sought evidence of mild or asymptomatic H5N1 infection by examining H5N1-specific T-cell and antibody responses in a high-risk cohort in Vietnam.
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Methods: Peripheral blood mononuclear cells were tested using interferon-... - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1093/infdis/jir689
-
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- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Journal of Infectious Diseases Journal website
- Volume:
- 205
- Issue:
- 1
- Pages:
- 20-27
- Publication date:
- 2011-11-11
- Acceptance date:
- 2011-08-09
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- Pubs id:
-
pubs:206077
- URN:
-
uri:0033a61e-3bcd-45e4-8a6f-8d7391ea9cd4
- UUID:
-
uuid:0033a61e-3bcd-45e4-8a6f-8d7391ea9cd4
- Local pid:
- pubs:206077
- Copyright holder:
- Powell et al.
- Copyright date:
- 2011
- Notes:
- © The Authors 2011. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved
Journal article
Identification of h5n1-specific t-cell responses in a high-risk cohort in Vietnam indicates the existence of potential asymptomatic infections
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077078/Z/05/Z/Wellcome Trust
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081613/Z/06/Z/Wellcome Trust
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G0600520/Medical Research Council
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Medical Research Council
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G1000800f/Medical Research Council
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