- Abstract:
-
BACKGROUND: Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice, although evidence from Asia suggests that artesunate is associated with a lower mortality. We compared parenteral treatment with either artesunate or quinine in African children with severe malaria. METHODS: This open-label, randomised trial was undertaken in 11 centres in nine African countries....
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s0140-6736(10)61924-1
-
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- Journal:
- Lancet
- Volume:
- 376
- Issue:
- 9753
- Pages:
- 1647-1657
- Publication date:
- 2010-11-05
- DOI:
- EISSN:
-
1474-547X
- ISSN:
-
0140-6736
- URN:
-
uuid:001333c7-cd92-44ac-972e-2044db2f5ac9
- Source identifiers:
-
93210
- Local pid:
- pubs:93210
- Copyright date:
- 2010
Journal article
Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial.
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