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Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic acid.

  • McKenna, CE, Kashemirov, BA, Błazewska, KM, et al.
  • 2010-05-05
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N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis.

  • Nuti, E, Casalini, F, Avramova, SI, et al.
  • 2009-08-05
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Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.

  • Dunford, JE, Kwaasi, AA, Rogers, MJ, et al.
  • 2008-04-05
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Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate.

  • Marma, MS, Xia, Z, Stewart, C, et al.
  • 2007-11-05
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