Investigation of the neural correlates of ongoing pain states using quantitative perfusion arterial spin labelling

Thesis

At present, there are few clinically effective pain therapies available to treat chronic pain. One reason is due to a lack of understanding about how pain emerges in the brain. Excitingly, an emerging body of work suggests that the perfusion imaging technique, arterial spin labelling (ASL), is particularly well-suited to investigate this issue. The primary aim of this thesis is to develop and optimise a quantitative perfusion imaging approach to investigate the neural correlates of both ex...

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Authors: Segerdahl, AR

• Publication date: 2011
• DOI: 10.5287/ora-b7aqdzx9b
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: functional magnetic resonance imaging; pain neuroscience; chronic pain imaging; arterial spin labelling; pain imaging
• Subjects: Neuroscience; Medical Sciences; Cognitive Neuroscience; Anaesthetics