Thesis
Definition of the early HIV-1 signalosome in dendritic cells
- Abstract:
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DCs are critical to the early events of HIV-1 infection. They are the first cells that HIV-1 encounters at mucosal surfaces and as sentinel antigen-presenting cells of the immune system these should alarm the immune system and activate innate immune defences to recruit effective adaptive immunity and viral clearance. A peculiar characteristic of HIV – in contrast to other ssRNA viruses – is its ability to completely evade host innate recognition pathways. Additionally, it has the unique ab...
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- Files:
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(bin, 13.5MB, Terms of use)
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Authors
Contributors
+ Simmons, A
- Division:
- MSD
- Department:
- NDM
- Role:
- Supervisor
+ Rowland-Jones, S
- Division:
- MSD
- Department:
- NDM
- Role:
- Supervisor
- Publication date:
- 2013
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
- Language:
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English
- Keywords:
- Subjects:
- UUID:
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uuid:e504a1b9-f8c0-455e-a61b-27c29b5adcdf
- Local pid:
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ora:7519
- Deposit date:
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2013-10-28
- ARK identifier:
Terms of use
- Copyright holder:
- Khatamzas, E
- Copyright date:
- 2013
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