Thesis
Identification of immunological targets for HIV-1 vaccine and cure strategies
- Abstract:
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HIV-1 chronically infected individuals represent a large disease burden, making the development of a therapeutic vaccine for use in chronic infection a priority. However, therapeutic vaccination has not been successful to date. Most approaches have employed viral vectored vaccines encoding full length viral proteins, which aimed to boost pre-existing CD8+ T cell responses by mimicking natural HIV-1 infection. Simply boosting these pre-existing CD8+ T cell responses which ...
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- Files:
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(Preview, Dissemination version, bin, 15.2MB, Terms of use)
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Authors
Contributors
+ Dorrell, L
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- NDM
- Role:
- Supervisor
- Publication date:
- 2014
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Keywords:
- Subjects:
- UUID:
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uuid:de163905-a755-43f1-b0c3-fdd737a2cf5b
- Local pid:
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ora:11785
- Deposit date:
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2015-07-02
- ARK identifier:
Terms of use
- Copyright holder:
- Gemma Hancock
- Copyright date:
- 2014
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