Journal article
Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom 1R ApcMin/+ mice
- Abstract:
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Ionising radiation is a carcinogen capable of inducing tumours, including colorectal cancer, in both humans and animals. By backcrossing a recombinant line of ApcMin/+ mice to the inbred BALB/c mouse strain, which is unusually sensitive to radiation-induced tumour development, we obtained panels of 2Gy-irradiated and sham-irradiated N2 ApcMin/+ mice for genotyping with a genome-wide panel of microsatellites at ∼15 cM density and phenotyping by counting adenomas in the small intestine. Interva...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 171.4KB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0004388
Authors
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLoS ONE More from this journal
- Volume:
- 4
- Issue:
- 2
- Publication date:
- 2009-02-05
- Acceptance date:
- 2008-12-22
- DOI:
Item Description
- Language:
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English
- UUID:
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uuid:d120408d-cdfe-4f8c-b27d-64ac6d51b6ab
- Local pid:
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pubs:440930
- Source identifiers:
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440930
- Deposit date:
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2014-02-08
Terms of use
- Copyright holder:
- Elahi et al
- Copyright date:
- 2009
- Notes:
- © 2009 Elahi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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