Thesis
Mathematical modelling of Centrosomin incorporation in Drosophila centrosomes
- Abstract:
-
Centrosomin (Cnn) is an integral centrosomal protein in Drosophila with orthologues in several species, including humans. The human orthologue of Cnn is required for brain development with Cnn hypothesised to play a similar role in Drosophila. Control of Cnn incorporation into centrosomes is crucial for controlling asymmetric division in certain types of Drosophila stem cells. FRAP experiments on Cnn show that Cnn recovers in a pe- culiar fashion, which suggest that Cnn may be incorporated...
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Authors
Contributors
+ Maini, P
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Mathematical Institute
- Role:
- Supervisor
+ Gaffney, E
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Mathematical Institute
- Role:
- Supervisor
+ Baker, R
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Mathematical Institute
- Role:
- Supervisor
+ Fletcher, A
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Mathematical Institute
- Role:
- Supervisor
- Publication date:
- 2013
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- UUID:
-
uuid:baefde65-bc38-4a11-bd92-e2e4cccad784
- Local pid:
-
ora:8680
- Deposit date:
-
2014-06-24
Terms of use
- Copyright holder:
- Suruchi Dhananjay Bakshi
- Copyright date:
- 2013
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