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Thesis

The impact of host and therapy mediated selection on HIV-1 evolution

Abstract:

The Human immunodeficiency virus (HIV) pandemic has resulted in a heavy global disease burden, and clinically causes Acquired Immuno-Deficiency Syndrome (AIDS). The development of highly active antiretroviral therapy (HAART) has achieved remarkable control of the rapidly evolving HIV. However, HIV remains neither curable nor preventable by vaccine, and in the developing regions worst affected by HIV, HAART remains inaccessible to most patients. Furthermore, the change in both immunology an...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
The Peter Medawar Building for Pathogen Research
Oxford college:
Green Templeton College
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
Division:
MSD
Department:
NDM
Role:
Supervisor

Publication date:
2010
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK

Language:
English
Keywords:
Subjects:
UUID:
uuid:b49d0d79-75c9-4314-92ae-1f1789ac7d42
Local pid:
ora:5166
Deposit date:
2011-03-23

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