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Thesis

Three dimensional perfused cell culture for in vitro toxicity testing

Abstract:

This study describes the development of a novel method of three dimensional perfused cell culture for in vitro toxicity testing. Multiple parallel perfused microbioreactors (TissueFlexTM) were adopted to provide a well-controlled cell culture environment. Alginate and collagen type I, commonly used as hydrogel scaffolds to support cell culture, were tested as the scaffolding materials for this application. Alginate supports cell proliferation, but does not support cell attachmen...

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Oxford college:
St Cross College
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Supervisor

Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Language:
English
Keywords:
Subjects:
UUID:
uuid:a72b7015-cc57-4bb8-904a-a5a88e2194f1
Local pid:
ora:11790
Deposit date:
2015-07-03

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