Relaxation processes in cardiac muscle

Thesis

The technique of laser flash photolysis was used in conjunction with diazo-2 to investigate the relaxation kinetics of skinned trabeculae from the guinea-pig. Diazo-2 is a caged Ca²⁺ chelator, based on BAPTA, which undergoes a rapid photochemical conversion (> 2000s^-1), when exposed to ultraviolet light, from a Ca²⁺ chelator with low affinity (K_d=2.2μM) to one with a higher affinity (K

Expand abstract

Authors: Simnett, S; Sarah Jacqueline Simnett

• Publication date: 1993
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Subjects: Heart; Physiological effect; Calcium ions; Myocardium; Metabolism; Contractility (Biology)