Thesis
A computational framework for understanding the dynamics of signalling pathways
- Abstract:
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Signalling pathways are subcellular networks that enable the cell to respond to its microenvironment. Abnormal function of a signalling pathway is a hallmark of carcinogenesis and developmental diseases. The signalling cascades in these pathways involve biochemical interactions that can lead to highly nonlinear cellular responses. Studies of signalling pathways often involve the proposal of models based on experimental data that are difficult to quantify and reproduce. Due to the nature of...
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- Files:
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(Preview, pdf, 13.2MB, Terms of use)
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Authors
Contributors
+ Fletcher, A
- Role:
- Supervisor
+ Pitt-Francis, J
- Role:
- Supervisor
+ Byrne, H
- Role:
- Supervisor
+ Gavaghan, D
- Role:
- Supervisor
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- UUID:
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uuid:85851162-c01d-4895-9f1e-5ea80f4b948a
- Deposit date:
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2018-05-31
- ARK identifier:
Terms of use
- Copyright holder:
- Cigari, A
- Copyright date:
- 2017
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