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Thesis

The temporal and geographical distribution and diversity of disease-associated Neisseria meningitidis genetic types in Europe

Abstract:

Meningococcal disease, caused by the bacterium Neisseria meningitidis, is an important cause of morbidity and mortality in young children and adolescents worldwide. There are 12 serogroups with most disease due to meningococci expressing one of five capsular polysaccharide antigens corresponding to serogroups A, B, C, Y and W135. In Europe, the majority of disease-causing strains are of serogroups B and C. No comprehensive vaccine is available against the bacterium due to the difficulty in pr...

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Research group:
Professor Martin Maiden
Oxford college:
Hertford College
Role:
Author

Contributors

Division:
MPLS
Department:
Zoology
Role:
Supervisor


Publication date:
2010
DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK


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