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Thesis

Electrophysiological effects of fentanyl, halothane and isoflurane on guinea-pig isolated ventricular myocytes

Abstract:
Ischaemic periods which lust only several minutes can result in a reversible reduction in cardiac contractility known as cardiac stunning. This is a potentially dangerous condition since arrhythmias and left ventricular failure are common in the stunned heart. The anaesthetics fentanyl, halothane and isoflurane have been shown to improve recovery from cardiac stunning (1,2). In this project the electrophysiological effects of these anaesthetics on guinea-pig isolated ventricular myocytes were investigated to determine the mechanisms underlying their cardioprotective effect.

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Institution:
University of Oxford
Division:
MSD
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Role:
Supervisor


Publication date:
2002
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
Subjects:
UUID:
uuid:58f6f4e2-aaa9-4913-a7c2-5568e2f8d72f
Local pid:
td:602828948
Source identifiers:
602828948
Deposit date:
2013-01-18

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