Novel methods in imaging mass spectrometry and ion time-of-flight detection

Thesis

Imaging mass spectrometry (IMS) in microscope mode allows the spatially resolved molecular constitution of a large sample section to be analysed in a single experiment. If performed in a linear mass spectrometer, the applicability of microscope IMS is limited by a number of factors: the low mass resolving power of the employed ion optics; the time resolution afforded by the scintillator screen based particle detector and the multi-hit capability, per pixel, of the employed imaging sensor. ...

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Authors: Winter, B

• Publication date: 2014
• DOI: 10.5287/ora-9obdpq8vo
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: mass spectrometry; particle detection; imaging mass spectrometry
• Subjects: Spectroscopy and molecular structure; Laser Spectroscopy; Microscopy; Surface analysis; Mass spectrometry