An anatomical model of the cerebral vasculature and blood flow

Thesis

The brain accounts for around 2 % of human adult bodyweight but consumes 20 % of the resting oxygen available to the whole body. The brain is dependent on a constant supply of oxygen to tissue, transported from the heart via the vasculature and carried in blood. An interruption to flow can lead to ischaemia (a reduced oxygen supply) and prolonged interruption may result in tissue death, and permanent brain damage.

The cerebral vasculature consists of many, densely packed, micro-vess...

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Authors: Lucas, C

• Publication date: 2013
• DOI: 10.5287/ora-goo6vprko
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: cerebral; vasculature; stroke; moygenic; autoregulation; microvasculature
• Subjects: Mathematical modeling (engineering); Engineering & allied sciences; Biomedical engineering