Thesis
Studies on basement membrane permeation
- Alternative title:
- models of pathogenic mechanisms of glomerulonephritis
- Abstract:
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The effects of the biological cross-linker transglutaminase, the neutrophil oxidant hydrogen peroxide, and neutrophil proteinases on glomerular basement membrane permeability have been examined using an in vitro model of glomerular ultrafiltration. The main focus of the study lies in determining whether any of the test agents were able to render glomerular basement membrane more permeable to protein.
Guinea pig liver transglutaminase was used as a model enzyme to test for the effec...
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- Publication date:
- 1994
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Subjects:
- UUID:
-
uuid:22440bfc-e712-4f7c-a11d-2eed9b07bcb6
- Local pid:
-
td:603851146
- Source identifiers:
-
603851146
- Deposit date:
-
2014-07-22
Terms of use
- Copyright holder:
- Tein, M
- Copyright date:
- 1994
- Notes:
- This thesis was digitised thanks to the generosity of Dr Leonard Polonsky
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