Cardiac mechanical model personalisation and its clinical applications

Thesis

An increasingly important research area within the field of cardiac modelling is the development and study of methods of model-based parameter estimation from clinical measurements of cardiac function. This provides a powerful approach for the quantification of cardiac function, with the potential to ultimately lead to the improved stratification and treatment of individuals with pathological myocardial mechanics. In particular, the diastolic function (i.e., blood filling) of left ventricl...

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Authors: Xi, J

• Publication date: 2013
• DOI: 10.5287/ora-de91ydexj
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: Oxford University, UK
• Language: English
• Keywords: computational biology; biomechanics; cardiac modelling
• Subjects: Solid mechanics; Mathematical modeling (engineering); Computer science (mathematics); Biomedical engineering; Mechanical engineering; Biology and other natural sciences (mathematics); Cardiovascular disease; Mathematical biology