Thesis
Dissecting the genome-wide dynamic responses of the HIF transcriptional system
- Abstract:
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Hypoxia is an important stimulus for physiological processes such as development and adaptation to high altitude. It is also important in the pathology of many human diseases such as cancer, cardiovascular and diabetic disorders. The sequence-specific, heterodimeric transcription factor HIF (Hypoxia Inducible Factor) has been shown to play a key role in cellular adaptation to hypoxia. This work aimed to better understand the contribution of HIF to hypoxia-inducible gene expression thr...
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Actions
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
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uuid:0ccfa0d0-7f61-407e-adee-1631ea392a59
- Deposit date:
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2018-09-14
Terms of use
- Copyright holder:
- Sun, M
- Copyright date:
- 2018
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